Comparison between respondres and nonresponders in first-episode schizophrenia
| Title in English | Comparison between responders and nonresponders in first-episode schizophrenia |
|---|---|
| Authors | |
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | European Neuropsychopharmacology |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | first-episode schizophrenia; responders; nonresponders |
| Description | 1)to asses in details the psychopatology before and after the acute antipsychotic treatment, 2)to compare responders and nonresponders. Method used: Male patients consecutively (November 1997 to March 2004) hospitalised with first-episode schizophrenia (according to ICD 10) were included. Clinical assessment was performed using the Positive and Negative Syndrome Scale (PANSS) after admission (before treatment)and at discharge. The response rate (defined as minimally 30% reduction from baseline in the PANSS total score) was evaluated at discharge. After a baseline assessment all patients were treated openly by monotherapy with an antipsychotics, the doses were individualised. The statistical analysis was made by means of the t-test (the Wilcoxon matched-pairs test and testing for differences between means) |
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