Dynamika psychopatologie u prvních epizod schizofrenie
| Title in English | Psychopathology and treatment responsiveness of patients with first-episode schizophrenia |
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| Authors | |
| Year of publication | 2006 |
| Type | Article in Proceedings |
| Conference | Psychiatria pre prax |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | first-episode schizophrenia; treatment response; psychopathology; remission |
| Description | One hundred and four male patients hospitalized for the first time with the diagnosis of first-episode schizophrenia were comprehensively assessed on admission and discharge. Psychopathology, treatment response, and remission rater were evaluated. On admission, the most frequently observed symptoms were lack of judgment and insight, suspiciousness, conceptual disorganization, and active social avoidance. Except for negative symptoms, and comceptual disorganization correlated with the greatest number of discharge, the most frequent symptoms were again lack of judgment and insight,and for negative symptoms they were blunted affect, emotional withdrawal, and passive/apathetic social withdrawal. The positive symptoms of suspiciousness feelings of persecution and grandiosity persisted in of patients. On average, all symptoms were significantly reduced 44 days after admission. The negative symptoms improved less, compared with the positive ones. At discharge there was a high rate of responders: 73% and 74% of patients fulfilled the criteria for remission. On admission, the responders (n=76) had significantly higher scores of most symptoms, both positive and negative ones than nonresponders (N=28) |
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