Použití makarpinu ke klasifikaci buněk průtokovou cytometrií.

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Title in English Use of macarpine in flow cytometry cell clasification
Authors

SLANINOVÁ Iva ŠINKORA Jiří TÁBORSKÁ Eva SLANINA Jiří SLAVÍK Jiří

Year of publication 2006
Type Patent
MU Faculty or unit

Faculty of Medicine

Publisher Úřad průmyslového vlastnictví
State Czech Republic
Patent's number 297482
Description We have proved that macarpine (MA) stains nucleic acids. MA, briefly enter living cells and interact with DNA. MA bind DNA stochiometrically and can report the DNA content at a resolution level adequate for cell cycle analysis. MA can also be used as supravital fluorescent DNA probe both in fluorescence microscopy and flow cytometry including multiparameter analysis of peripheral blood and bone marrow.
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