Cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons - Structure-Activity Relationships.

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Authors	SOVADINOVÁ Iva BLÁHA Luděk JANOŠEK Jaroslav HILSCHEROVÁ Klára GIESY J. JONES P.D. HOLOUBEK Ivan
Year of publication	2006
Type	Article in Periodical
Magazine / Source	Environmental Toxicology and Chemistry
MU Faculty or unit	Faculty of Science
Citation
Field	Environment influence on health
Keywords	Cytotoxicity;Aromatic Hydrocarbons
Description	This study presents results of cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons along with their parental compounds determined in a model in vitro system. Structure-Activity Relationship was performed to determine the structural features of the compounds related to the observed effects.
Related projects:	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL) In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants