Profilování genové exprese u mnohočetného myelomu

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Title in English Gene expression profiling in multiple myeloma
Authors

DUDOVÁ Silvie BÁRTOVÁ Eva POUR Luděk KREJČÍ Jana HÁJEK Roman

Year of publication 2006
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords DNA microarray; gene expression profile; chromatin immunoprecipitation; multiple myeloma
Description This review informs about utilization of two methods used in molecular examination in multiple myeloma on genomic level: DNA microarrays and chromatin immunoprecipitation. The profit of both methods is very similar in myeloma as well as in other cancers. They allow to study disease pethogenesis, generate new disease classification, and try to predict effect of therapy. Also, they are used to find the new potential target of therapy in multiple myeloma.
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