Porovnání standardních prognostických faktorů u pacientů studie CMG 2002 s delecí 13q14 stanovenou molekulárně cytogenetickými metodami
| Title in English | Correlation between the prognostic factors and the deletion of 13q14 using the molecular cytogenetic methods in the group of patiens from the CMG 2002 clinical study |
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| Authors | |
| Year of publication | 2006 |
| Type | Monograph |
| MU Faculty or unit | |
| Citation | |
| Description | Cytogenetic abnormalities in multiple myeloma (MM) are one of the most important independent prognostic factors. The aim was to determine the correlation between the aberration of the chromosome 13 (detected by molecular cytogenetic methods) and the prognostic factors in the pilot group of patients from the CMG 2002 clinical study (only data from one clinical centre covers 1/4 of patients) using three various of cut off levels (9%, 20%, 80%). Higher MIG and lower albumin concentrations and platelet counts (for cut off level 80%) were detected in patients with aberration of chromosome 13 (cut off levels 9%, 20%). This analysis will be extended for all centres of CMG 2002. |
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