Role of cannabinoid CB1 receptor inhibition in regulation of anxiety and depression related behaviours in mice
| Authors | |
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| Year of publication | 2007 |
| Type | Article in Proceedings |
| Conference | Programme and Abstracts, 9th International Neuroscience Winter Conference |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | CB1 receptor antagonists; anxiety; depression; mice |
| Description | Two CB1 receptor antagonists rimonabant and AM251 showed just tendency to increase aggressive activities mice, without any other significant behavioural changes in the timid mice, that means no anxiolytic effects. However, our findings confirmed that rimonabant may have a suggested beneficial effect on depression and social stress-related behaviour. |
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