Behavioural sensitization to methamphetamine is associated with cannabinoid CB1 receptors downregulation in the rat brain VTA

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Authors	ŠULCOVÁ Alexandra DUBOVÝ Petr KUČEROVÁ Jana
Year of publication	2007
Type	Article in Periodical
Magazine / Source	Behavioural Pharmacology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	methamphetamine; behavioural sensitization; CB1 receptor downregulation
Description	On comparison to the control animals the significantly decreased density of cannabinoid CB1 receptors on neuronal membranes of the VTA immunofluorescent detection) was found in methamphetamine treated rats.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.