Vliv polymorfismu C5266T v genu pro nNOS na variabilitu v srdečním intervalu.

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Title in English	Influence of C5266T polymorphism in nNOS gene on inter-beat interval variability
Authors	JÍRA Miroslav ZÁVODNÁ Eva HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana VAŠKŮ Anna IZAKOVIČOVÁ HOLLÁ Lydie FIŠER Bohumil
Year of publication	2007
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Reduced inter-beat interval variability represents independent indicator of adverse prognosis in patients after myocardial infarction. The aim of this study was to evaluate association of single nucleotide polymorphism C5266T in gene encoding nNOS with heart period variability in men. We found significant association of C5266T polymorphism in gene encoding nNOS with heart period variability. The presence of allele T represents protective factor against sympathetic overactivity.
Related projects:	Early diagnostics and treatment of cardiovascular diseases