Pyrosequencing as a tool for whole genome sequencing of Treponema pallidum subspecies.
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Chemické Listy |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.chemicke-listy.cz/docs/full/2007_05_425-465.pdf |
| Field | Genetics and molecular biology |
| Keywords | pyrosequencing; Treponema pallidum |
| Description | Treponema pallidum includes several obligate human pathogens. T. p. pallidum is an agent of sexually transmitted syphilis, T. p. pertenue and T. p. endemicum causes yaws and endemic syphilis, respectively. Pyrosequencing (454 sequencing) is a massivelyparallel sequencing-by-synthesis system. In this study, genomic DNA of T. p. pertenue CDC-2 was completely sequenced using 454 technology. |
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