Úspěšná léčba prokázané kandidové peritonitidy za použití efungumabu (mycocrab) u dítěte s abdominálním non-hodgkinským lymfomem.
| Title in English | Successful treatment of the proven candida peritonitis in child with abdominal Non-Hodgkin´s lymphoma using efungumab ( Mycograb ). |
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| Authors | |
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Klinická onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | candidiasis children lymphoma antigungal therapy monoclonal antibodies |
| Description | Case report regarding the first successful use of efungumab in a child with cancer in Europe.Invasive fungal infections represent a relatively fequent and serious complication of the treatment in cancer patients. Fungal peritonitis forms a complicated subgroup of them and has been connected with a high mortality rate. We present a case reprt of a 12 year old boy diagnosed with abdominal NHL and proven Candida sp. peritonitis as an early onset complication of the induction chemotherapy. The invasive mycosis has been seccesfully managed using a combined approcachof systemic antifungal agents, surgical interventions and monoclonal antibody efungumab (Mycograb). We present our own experience with this novel drug in a pediatric patient. A wide collaboration between specialists is accented, and therapeutic options in invasive fungal nfections are discussed. |
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