The combined effect of ultrasound exposure and cisplatin on human ovarian carcinoma cells A2780
| Authors | |
|---|---|
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Folia Biologica (Praha) |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | cisplatin; cytotoxicity; ovarian carcinoma cells A2780; ultrasound |
| Description | It was shown that a combined effect of ultrasound and cisplatin was more effective than that of ultrasound or cisplatin alone. It also appeared that the order of application played a role, with the cisplatin-ultrasound treatment lowering cell viability more than the ultrasound-cisplatin treatment. It can be assumed that the exposure of cells to a low-power ultrasonic field has an immediate effect on the structure of cell surfaces and, consequently, on entry of cisplatin into the cell. |
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