Elimination Voltammetry of Oligonucleotides

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Authors

TRNKOVÁ Libuše MIKELOVÁ Radka JELEN František ADAM Vojtěch KIZEK René

Year of publication 2008
Type Article in Proceedings
Conference Electrochemistry of Nucleic Acids and Proteins. Book of Abstracts
MU Faculty or unit

Faculty of Science

Citation
Field Electrochemistry
Keywords oligonucleotide; voltammetry; EVLS
Description EVLS can be considered as a mathematical model of the transformation of current-potential curves capable of eliminating some selected current components, while conserving others by means of elimination functions. The present contribution summarizes applications of EVLS to the study of oligonucleotides (ODNs) with different sequences of cytosine (C) and adenine (A). The EVLS offers a new tool for very good resolution of A and C in ODNs, and, thus, for a qualitative and quantitative sensing of changes in primary structure of ODN chains.
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