Stanovení hyperdiploidií u mnohočetného myelomu pomocí imunofluorescenčního značení plazmatických buněk a techniky tříbarevné interfázní FISH

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Title in English	Detection of hyperdiploidy in patients with multiple myeloma using immunofluorescent staining of plasma cells and three-color interphase FISH technique
Authors	SMETANA Jan KUGLÍK Petr GREŠLIKOVÁ Henrieta KUPSKÁ Renata FILKOVÁ Hana OLTOVÁ Alexandra HÁJEK Roman
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Klinická onkologie
MU Faculty or unit	Faculty of Medicine
Citation
Web	http://www.linkos.cz/vzdelavani/Supp1_08/08.pdf
Field	Oncology and hematology
Keywords	multiple myeloma; cytogenetics; FISH; hyperdiploidy
Description	We focus on the applications of immunofluorescent staining of tumor plasma cells and three-color interphase in situ hybridization with specific DNA probes for chromosome 5, 9, and 15 for the detection of hyperdiploidy in patients with multiple myeloma.
Related projects:	Molecular basis of cell and tissue regulations University Research Centre - Czech Myeloma Group From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies