Histiocytóza z Langerhansových buněk u osob dospělého věku - nemoc s mnoha tvářemi.Zkušenosti jednoho pracoviště a přehled projevů nemoci.

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Title in English Langerhans cell histiocytosis in adult patients--a disease with many faces. Experience of a centre and an overview of the disease symptoms
Authors

ADAM Zdeněk POUR Luděk KREJČÍ Marta NEUBAUER J. VANÍČEK J. VAŠKŮ V. HÁJEK Roman

Year of publication 2008
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords histiocytosis
Description The occurrence of LCH at adult age is rare and the disease may affect the skeleton as well as other organs. Therefore each new osteolytic lesion should be submitted for histological exam, as well as each pathologic formation, because diagnosing the disease without a microscopic and immunohistochemical exams is not possible. In the case of occurrence of diabetes insipidus at adult age, LCH should be considered as one of the possible underlying diseases. LCH pulmonary involvement should be considered in patients with an interstitial pulmonary process and the examinations should be focused accordingly (thoracoscopy with sampling for histological exams or bronchoalveolar lavage) plus the indispensable immunohistochemical examination.
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