CHROMATIN ASSOCITED HMGB1 PROTEIN IS INVOLVED IN REGULATION OF TELOMERE LENGTHS IN PLANTS

Warning

This publication doesn't include Faculty of Arts. It includes Faculty of Science. Official publication website can be found on muni.cz.

Authors	PROCHÁZKOVÁ SCHRUMPFOVÁ Petra GRASSER Klaus FAJKUS Jiří
Year of publication	2009
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	High Mobility Group (HMG) proteins type B bind local DNA structures, promote DNA bending and interact with factors of the transcription, repair and recombination machineries. Arabidopsis thaliana genome encodes 7 HMGB proteins which differ in structure, expression pattern and DNA-binding properties. We observe that HMGB1 takes part in telomere maintenance. Plants lacking HMGB1 display telomere shortening and, consistently, overexpression of HMGB1 leads to telomere elongation.
Related projects:	Molecular basis of cell and tissue regulations Understanding of HMGB1 protein involvement in maintaining genome stability Characterisation of functional diversity of the plant-specific SMH family of proteins