Diferenciální diagnostika eozinofilie
| Title in English | Diferential diagnosis of eosinophilia |
|---|---|
| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | eosinophilia; hypereosinophilic sndrome; eosinophilic leukaemia |
| Description | Elevated eosinophil count might be a sign of many different pathologies. most frequently, this is a result of allergic conditions. Elevated eosinophil count associated with a parasitic infection is considered as physiological. Eosinophilia may be linkded to certain organ and connective tissue disorders. The primary increase in eosinophil count may be caused by pathologic (bengin or malignant) cloning of T-lymphocytes that, though their cytokines, stimulate proliferation and differentiation of eosinophilic lineage. Nonetheless, the primary malfunction could also be directly in the myeloid cell line. Some of the myeloid cell mutations associated with uncontrolled eosinophilic myeloproliferation have been described, others are awaiting identification. The aim of this paper i to describe all states that result in elevated peripheral blood eosinophil count and provide directions for differential diagnosis. |
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