Následné primární novotvary u 125 262 onkologicky nemocných v České republice 1976-2005

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Title in English Subsequent primary neoplasms in 125 262 cancer patients in the Czech Republic 1976-2005
Authors

GERYK Edvard DÍTĚ Petr PEŠEK Miloš KOZEL Jiří

Year of publication 2009
Type Article in Periodical
Magazine / Source Onkologie
MU Faculty or unit

Faculty of Science

Citation
Web http://www.onkologiecs.cz
Field Earth magnetism, geography
Keywords multiple neoplasms; cartography
Description During 1976-2005 the Czech Cancer Registry registered 1.486,984 neoplasms dg. C00-D48, of which in 125,262 (8,4 %) cancer patients were diagnosed 165,050 (11,1 %) subsequent neoplasms. There were treated 81.7 % patients of duplicities and 18.3 % of multiplicities. There were higher duplicities in women and on the contrary higher multiplicities in men. The age groups 50-69 years contributed most to 52.4 % primary diseases in men and 47.8 % in women. Their most frequent occurence were in regions Northern and Southern Moravia and Prague. The most frequent of primary diseases were tumors of skin 42.8 %, digestive 11.8 %, urinary 6.8 % and respiratory system 4.8 %, breast 8.4 %, female 7 % and male genital tract 4.2 %. The average length between the primary and subsequent diseases was 6 years in men and 6.6 years in women. During the first year after primary disease occured 15,602 (17.4 %) subsequent neoplasms in men and 11,689 (15.5 %) in women. The proportion of synchronous and metachronous disease was 1:4.8 in men and 1:5.4 in women. From 125,262 patients died 84,101 (29.9 % men, 27.9 % women) and survived 41,161 (12,2 % men, 16,5 % women) as of 17. 10. 2007. The numbers of died from primary neoplasms increased till 1994-1995 and survived till 2002, then decreased. From the presented data follows the necessity of screening programmes and importace of sufficient long permanent medical surveillance, especially in view of multiple primary and subsequent solid tumors and the most frequent cancers of skin. The broad public information and education of the first cancer symptoms and improving of life-style is not yet sufficient both for healthy population and for 395,547 treated patients with cancers in 2005.
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