Léčba selhání ledvin u mnohočetného myelomu

Warning

This publication doesn't include Faculty of Arts. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Title in English The treatment of renal failure in multiple myeloma
Authors

ADAM Zdeněk KREJČÍ Marta TICHÝ M. ŠTĚPÁNKOVÁ S. POUR Luděk HÁJEK Roman

Year of publication 2009
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords multiple myeloma; renal faiklure
Description While in some patients, renal failure is the only, isolated sign of multiple myeloma, other patients have further simultaneous symptoms (signs of bone destruction, hypercalcaemia, cytopenia). Therefore, differential diagnosis of renal failure should always include monoclonal gametopathy-associated nephropathy. Renal damage is caused dominantly by free light chains. Elevated early mortality reaches 30% during the first 3 months and complicates treatment of patients with multiple myeloma with renal failure. More serious the renal damage caused by monoclonal immunoglobulin is, less likely is the improvement of renal function following treatment. Early diagnosis at the time when renal impairment is still reversible is extremely important for the patient's prognosis.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.