Studie možností ovlivnění antineoplastického efektu retinoidů jejich kombinovanou aplikací s LOX/COX inhibitory na modelu neuroblastomových buněčných linií.

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Title in English	Study of possibilities to modulate the antineoplastic effect of retinoids by their combined application with LOX/COX inhibitors in neuroblastoma cell lines.
Authors	RÉDOVÁ Martina CHLAPEK Petr LOJA Tomáš ZITTERBART Karel HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2009
Type	Article in Proceedings
Conference	XIX. Konferencia detských hematológov a onkologov Českej a Slovenskej republiky - zborník abstraktov
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	neuroblastoma; medulloblastoma; established cell lines; caffeic acid; celecoxibe; all-trans retinoic acid; cell differentiation
Description	A detailed study of the effect of combined application of the LOX/COX inhibitors with ATRA in established neuroblastoma cell lines was performed using MTT-assay, immunoblotting, and flow cytometry.
Related projects:	Molecular basis of cell and tissue regulations Modulace antineoplastického efektu retinoidů LOX/COX inhibitory na modelu dětských solidních nádorů: in vitro studie Molecular mechanisms of the cell proliferation and differentiation