One-pot, three-component synthesis of five-membered cyclic nitrones by addition/cyclization/condensation domino reaction
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Tetrahedron |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Keywords | Allenes;allenyloxime;cyclic nitrones;heterocyclizations;one-pot;domino reactions |
| Description | A new approach to five-membered cyclic nitrones connected with the incorporation of a planar aromatic ring system into the structure is described. This procedure is based on an allenyloxime one-pot domino transformation under simple base catalysis in alcoholic and aqueous solvents. The structure of obtained nitrones was studied by X-ray analysis and the reactivity of products in 1,3-dipolar cycloadditions was tested. |
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