Optimization of immunomagnetic selection of myeloma cells from bone marrow using magnetic activated cell sorting
Authors | |
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Year of publication | 2010 |
Type | Article in Periodical |
Magazine / Source | International journal of hematology |
MU Faculty or unit | |
Citation | |
Web | http://www.ncbi.nlm.nih.gov/pubmed/20694533 |
Field | Oncology and hematology |
Keywords | multiple myeloma; immunomagnetic separation; plasma cell; CD138 |
Description | Plasma cells (PCs) enrichment from bone marrow samples of multiple myeloma (MM) patients is frequently performed by immunomagnetic separation (magnetic activated cell sorting, MACS) using anti-CD138 MicroBeads. The aim of our work was to find optimal strategy for immunomagnetic separation of PCs and determine optimal algorithm of separation techniques for samples with various percentage of neoplastic cells. |
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