Analysis of the host-parasite interactions in gastric pathogen Cryptosporidium muris

Investor logo

Warning

This publication doesn't include Faculty of Arts. It includes Faculty of Science. Official publication website can be found on muni.cz.
Authors

ILGOVÁ Jana VALIGUROVÁ Andrea

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description Cryptosporidium (Apicomplexa) is an epicellular parasite infecting gastrointestinal tract of vertebrates, including humans. Cryptosporidiosis is self-limiting disease in healthy hosts; however, it represents a life-threatening problem in immunocompromised individuals because of lack of an effective treatment. The aim of presented study was to examine and optimise procedures, such as rodent inoculation, faeces examinations, oocysts purification and excystation in vitro, for the planned in vitro and in vivo analyses of host-parasite interactions in Cryptosporidium muris. Additional histological observations have been performed to observe pathological effect of parasite on experimentally infected immunocompromised laboratory mice.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.