Analysis of the host-parasite interactions in gastric pathogen Cryptosporidium muris

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Authors	ILGOVÁ Jana VALIGUROVÁ Andrea
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Cryptosporidium (Apicomplexa) is an epicellular parasite infecting gastrointestinal tract of vertebrates, including humans. Cryptosporidiosis is self-limiting disease in healthy hosts; however, it represents a life-threatening problem in immunocompromised individuals because of lack of an effective treatment. The aim of presented study was to examine and optimise procedures, such as rodent inoculation, faeces examinations, oocysts purification and excystation in vitro, for the planned in vitro and in vivo analyses of host-parasite interactions in Cryptosporidium muris. Additional histological observations have been performed to observe pathological effect of parasite on experimentally infected immunocompromised laboratory mice.
Related projects:	Diversity of Biotic Communities and Populations: Causal Analysis of variation in space and time Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa