Association of polymorphisms of zinc metalloproteinases with clinical response to stem cell therapy

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Authors

PANOVSKÝ Roman VAŠKŮ Anna MELUZÍN Jaroslav KAMÍNEK Milan MAYER Jiří JANOUŠEK Stanislav KINCL Vladimír GROCH Ladislav NAVRÁTIL Milan

Year of publication 2010
Type Article in Periodical
Magazine / Source Herz Cardiovascular Diseases
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords coronary artery disease; stem cells; polymorphism; metalloproteinases
Description In our study, the ACE genotype II was associated with improvement of regional systolic LV function of the infarcted wall after implantations of MBMC. The detected polymorphism in matrix metalloproteinase-2 gene was not associated with clinical response to cell therapy.
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