Souvislost genetických faktorů s rozvojem kardiovaskulárních onemocnění u sportovců

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Title in English	Connection of genetic factors with the development of cardiovascular diseases in sportsmen
Authors	JÍRA Miroslav VYSOKÝ Robert VOMELOVÁ Naděžda VOMELA Jindřich ZÁVODNÁ Eva
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Medicina Sportiva Bohemica Slovaca
MU Faculty or unit	Faculty of Medicine
Citation
Field	Physiology
Keywords	training; cardiovascular diseases; polymorphism A1166C; AT1 receptor; polymorphismus T-786C and G894T; eNOS
Description	The aim of this study was to evaluate the association of polymorphisms in genes pivotal for cardiovascular diseases with hemodynamic parameters (BRS, BPV) and point at possible risk factors for development of these diseases in sportsmen. A significant association of the studied polymorphism with monitored parameters was found. In active sportsmen, carriers of critical allels, their influence on alteration of cardiovascular system regulation, adaptation mechanisms and cardiovascular diseases development could be exerted.
Related projects:	Early diagnostics and treatment of cardiovascular diseases