Ztráta kopie genu pro EGFR u pacienta s multiformním glioblastomem: případová studie a analýza derivované linie.

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Title in English A loss of EGFR gene copy in glioblastoma multiforme: a case report and analysis of derived cell line.
Authors

NERADIL Jakub ŠKODA Jan LOJA Tomáš ZITTERBART Karel PAVELKA Zdeněk ŠMARDOVÁ Jana VALÁŠKOVÁ Iveta HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description This study is focused on the analysis of glioblastoma multiforme in patient experienced very long event-free survival after surgery and adjuvant radiotherapy and chemotherapy. Tumor tissue as well as derived HGG-02 cell line were analyzed using molecular biology and molecular cytogenetic methods. The most important finding is a loss of EGFR gene copy in both the tumor tissue and the HGG-02 cell line.
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