Ztráta kopie genu pro EGFR u pacienta s multiformním glioblastomem: případová studie a analýza derivované linie.

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Title in English	A loss of EGFR gene copy in glioblastoma multiforme: a case report and analysis of derived cell line.
Authors	NERADIL Jakub ŠKODA Jan LOJA Tomáš ZITTERBART Karel PAVELKA Zdeněk ŠMARDOVÁ Jana VALÁŠKOVÁ Iveta HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	This study is focused on the analysis of glioblastoma multiforme in patient experienced very long event-free survival after surgery and adjuvant radiotherapy and chemotherapy. Tumor tissue as well as derived HGG-02 cell line were analyzed using molecular biology and molecular cytogenetic methods. The most important finding is a loss of EGFR gene copy in both the tumor tissue and the HGG-02 cell line.
Related projects:	Molecular basis of cell and tissue regulations Diagnostický a prediktivní význam molekulárně cytogenetických markerů u embryonálních nádorů dětského věku Molecular mechanisms of the cell proliferation and differentiation