Schnitzler-syndrom: popis případu, zkušenosti s léčbou glukokortikoidy a preparátem anakinra (Kineret) a sledování cytokinové odpovědi organizmu

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Title in English Schnitzler syndrome: case report, the experience with glucocorticoid and anakinra (Kineret) therapies and monitoring of systemic cytokine response
Authors

SZTURZ Petr ADAM Zdeněk KLABUSAY Martin FOJTÍK Zdeněk KADAŇKA Zdeněk STEHLÍKOVÁ Olga CHOVANCOVÁ Jana KALVODOVÁ Libuše ČORBOVÁ Drahomíra STARÝ Karel NEUBAUER Jiří PRÁŠEK Jiří KOUKALOVÁ Renata ŘEHÁK Zdeněk HÁJEK Roman MAYER Jiří

Year of publication 2011
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords Schnitzler syndrome; autoinflammatory diseases; monoclonal gammopathy; multiple myeloma; Cushing's syndrome; interleukins
Description Schnitzler syndrome is a rare idiopathic disease characterized by chronic urtica, presence of monoclonal IgM immunoglobuline and further, less common symptoms. This case report describes another case of this disease affecting a male adult born in 1963. The first symptoms, eruptions of nonpruritic urticarial rash, appeared in this patient at the age of 43. In addition, bone pains (mainly tibias) and joint pains (mainly knees) were present. Later on however, severe attacks of fever, chills and shaking together with bone and joint pains were added to during which new urticarial eruptions appeared.
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