Estimation of left ventricular filling pressures by speckle tracking echocardiography in patients with idiopathic dilated cardiomyopathy

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Authors

MELUZÍN Jaroslav ŠPINAROVÁ Lenka HUDE Petr KREJČÍ Jan PODROUŽKOVÁ Helena PEŠL Martin ORBAN Marek DUŠEK Ladislav JARKOVSKÝ Jiří KOŘÍNEK Josef

Year of publication 2011
Type Article in Periodical
Magazine / Source European Journal of Echocardiography
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1093/ejechocard/jeq088
Field Cardiovascular diseases incl. cardiosurgery
Keywords Left ventricular filling pressure
Description Aims The ratio of early diastolic transmitral flow velocity (E) to early diastolic mitral annular velocity (Ea) is frequently used to predict an increase in left ventricular filling pressure (LVFP). However, this approach has several limitations. The aim of this study was to test whether additional information is gained by new echocardiographic indexes utilizing strain and strain rate (SR) derived from 2-dimensional speckle tracking echocardiography (2D-STE) for the estimation of LVFP. Methods and results Fifty-one patients with idiopathic dilated cardiomyopathy (IDC) underwent pulsed-wave tissue Doppler echocardiography and 2D-STE performed simultaneously with right heart catheterization. Receiver operating characteristic analysis showed that circumferential strain and the SR during late diastolic LV filling (0.956 and 0.951, both P = 0.001), E/circumferential SR at early diastolic LV filling (0.949, P = 0.001), and E/circumferential strain at the time of peak E-wave (0.948, P= 0.001) had greater area under the curve than the E/E(a) ratio (0.911, P = 0.001) for the prediction of pulmonary capillary wedge pressure > 12 mmHg.
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