Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene

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Authors

ODRÁŠKA Pavel DOLEŽALOVÁ Lenka PILER Pavel ORAVEC Michal BLÁHA Luděk

Year of publication 2011
Type Article in Periodical
Magazine / Source Journal of Environmental Monitoring
MU Faculty or unit

Faculty of Science

Citation
Web https://pubs.rsc.org/en/content/articlelanding/2011/EM/c0em00660b#!divAbstract
Doi http://dx.doi.org/10.1039/c0em00660b
Field Hygiene
Keywords antineoplastic drugs; cyclophosphamide; occupational exposure; ambient contamination; air analysis; solid-phase extraction
Description The main objective of the study was to evaluate applicability of two solid sorbent media (Anasorb 708 and Strata X), the impinger filled with distilled water and PTFE filters for determination of airborne cyclophosphamide in the hospital working environment (Masaryk Memorial Cancer Institute, Czech Republic). The study showed that Strata X solid sorbent is an effective tool for the sampling of gaseous cyclophosphamide in the indoor air. Using this sorbent, low levels of airborne cyclophosphamide were determined in the outpatient clinic.
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