Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures.
| Authors | |
|---|---|
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Toxicon |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1016/j.toxicon.2011.05.006 |
| Field | Environment influence on health |
| Keywords | Gap-junctional intercellular communication (GJIC); Exudate; Biomass; Cyanobacteria; Tumor promotion |
| Description | The extracts from different natural water blooms inhibited GJIC with different potencies without apparent relation to bloom-species composition. Since the observed effects on GJIC did not correlate with the content of cyanotoxins microcystins and cylindrospermopsin in the tested samples, they were most likely induced by unknown compound(s). Our results indicate that putative tumor promoting compound(s) could be associated with different species of bloom-forming cyanobacteria, but their production is probably species- and strain-specific. |
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