AIFM2 (apoptosis-inducing factor, mitochondrion-associated, 2)

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Authors

VAŘECHA Miroslav

Year of publication 2010
Type Article in Periodical
Magazine / Source Atlas of Genetics and Cytogenetics in Oncology and Haematology
MU Faculty or unit

Faculty of Informatics

Citation
Web http://documents.irevues.inist.fr/handle/2042/44747
Doi http://dx.doi.org/10.4267/2042/44747
Field Genetics and molecular biology
Keywords AIFM2;AMID;PRG3;mitochondria
Attached files
Description AIFM2 is oxidoreductase of 373 AA lenght. It is predicted to take part in caspase-independent apoptosis similarly to homologous AIFM1 (AIF, PDCD8). AIFM2 is p53-responsive gene and production of AIFM2 was found to be suppressed in many human cancers.
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