Project information
Proteiny HMGB: funkce v biologii telomer a lidských embryonálních kmenových buněk

Information

This project doesn't include Faculty of Arts. It includes Faculty of Medicine. Official project website can be found on muni.cz.

Project Identification

GAP305/12/2475

Project Period

1/2012 - 12/2015

Investor / Pogramme / Project type

Czech Science Foundation

Standard Projects

MU Faculty or unit

Faculty of Medicine

doc. MVDr. Aleš Hampl, CSc.

Cooperating Organization

Institute of Biophysics

Studovat vliv cílené deregulace exprese chromozomálních proteinů HMGB na aktivitu telomerázy, strukturu a funkci telomer, genomovou stabilitu a pluripotenci/diferenciaci lidských embryonálních kmenových buněk.

Publications

Total number of publications: 4

2017

Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins

BAGHERPOOR Alireza Jian DOLEŽALOVÁ Dáša BÁRTA Tomáš KUČÍREK Martin SANI Soodabeh Abbasi EŠNER Milan BOSÁKOVÁ Michaela VINARSKÝ Vladimír PEŠKOVÁ Lucie HAMPL Aleš ŠTROS Michal

Article in Periodical

Stem Cells and Development, year: 2017, volume: 26, edition: 5, DOI

2015

Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein

ŠTROS Michal POLANSKÁ Eva KUČÍREK Martin POSPÍŠILOVÁ Šárka

Article in Periodical

Plos one, year: 2015, volume: 10, edition: 9, DOI

2014

Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1

POLANSKÁ Eva POSPÍŠILOVÁ Šárka ŠTROS Michal

Article in Periodical

Plos one, year: 2014, volume: 9, edition: 2, DOI

2012

HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction

POLANSKÁ Eva DOBŠÁKOVÁ Zuzana DVOŘÁČKOVÁ Martina FAJKUS Jiří ŠTROS Michal

Article in Periodical

Chromosoma, year: 2012, volume: 121, edition: 4, DOI