Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2004
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Changes of immunofluorescence staining for ECM molecules in the rat dorsal root ganglia following chronic compression of the peripheral nerve
Journal of Molecular Histology, year: 2004, volume: 35, edition: 2
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Impact of cannabinoid CB2 receptor activity on aggressive behaviour in mice and senistization to methamphetamine antiaggressive effects.
Year: 2004, type: R&D Presentation
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Impact of phenotyping CYP2D6 in psychiatry
Psychiatrie, year: 2004, volume: 8, edition: suppl.4
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Interaction of cannabinoid methanandamide with processes of sensitization to both behavioral and immunological methamphetamine effects in mice.
Abstracts - NIDA International Forum 2004, San Juan, Puerto Rico, year: 2004
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Intracerebral ERP correlated with fMRI findings in the study of auditory oddball paradigms
Clinical Neurophysiology, year: 2004, volume: 115 (2004), edition: 8
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Intracerebral records of the bereitschaftspotential demonstrate non-homogenity of its early and late components
Homeostasis in Health and Disease, year: 2004, volume: 43/2004, edition: 2/2004
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Intracerebrally recorded ERPs in a frequency range of 5.5-15 Hz in visual oddball paradigm
Evoked Potentials International Conference XIV, year: 2004
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Involvement of 5-HT1 and 5-HT2 receptor activity in methamphetamine i.v. self-administration in rats depressed by olfactory bulbectomy
Fundamental & Clinical Pharmacology, year: 2004, volume: 18, edition: Suppl. 1
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Is there association between soft signs and clinical picture in schizophrenia?
European Neuropsychopharmacology, year: 2004, volume: 13, edition: 1
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Je možná farmakologická prevence Alzheimerovy choroby?
JAMA, year: 2004, volume: 12, edition: 6