Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2004
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Cross-sensitization with morphine to methamphetamine effects on locomotion in mice
Psychiatrie, year: 2004, volume: 8, edition: Suppl. 1
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Cross-sensitization with morphine to methamphetamine effects on locomotion in mice
Homeostasis in Health and Diseases, year: 2004, volume: 43, edition: 1
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Determination of Midazolam from Perfuse Medium as a Probe Substrate of Cytochrome P450 3A1/2 Activity in Rats
ACTA UNIVERISTATIS PALACKIANAE OLOMUCENSIS FACULTAS RERUM NATURALIUM, year: 2004
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Dotazníky a škály k měření sexuálních funkcí
Česká a Slovenská psychiatrie, year: 2004, volume: 100, edition: 8
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Effect of acute and sub-chronic administration of methamphetamine on metabolic activity of CYP2D1/2 in isolated perfused rat liver
Homeostasis, year: 2004, volume: 43, edition: 1
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Effect of St Johns wort extract LI 160 on metabolic activity of CYP2C6 in isolated perfused rat liver.
Homeostasis, year: 2004, volume: 43, edition: 1
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Effect of St. Johns wort (Hypericum perforatum) standardized extract on leukocyte phagocytosis in rat model of depression
Psychiatrie, year: 2004, volume: 8, edition: Suppl.4
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Effects of valproate on leukocyte phagocytosis in mice and in a rat model of depression
European Neuropsychopharmacology, year: 2004, volume: 14, edition: 3
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Encoding and hippocampal activation in patients with first-episode schizophrenia: a fMRI study
Neuropsychopharmacologia Hungarica, year: 2004, volume: 6, edition: 1
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Encoding in patients with first-episode schizophrenia: an fMRI trial
The International Journal of Neuropsychopharmacology, year: 2004, volume: 7, edition: 7