Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.

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Authors	REIGL Tomáš NAVRKALOVÁ Veronika PORC Jakub Paweł PÁL Karol STRÁNSKÁ Kamila POSPÍŠILOVÁ Šárka PLEVOVÁ Karla
Year of publication	2023
Type	Conference abstract
MU Faculty or unit	Central European Institute of Technology
Citation
Attached files	CEITEC_PhD_conference_Abstract_book.pdf
Description	High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research', he has been involved in the development of several software projects, e.g.: LYNX (LYmphoid NeXt-Generation Sequencing) analytical software, CLLue, ARResT/Interrogate, ARResT/Subsets aka Encyclopedia of CLL Subsets. LYNX is a tailor-made bioinformatic tool for a new custom-designed capture-based NGS panel. With this tool, a user can analyze molecular markers, such as gene mutations, copy number variations, antigen receptor rearrangements, and translocations in the most common lymphoid malignancies. CLLue is an interactive web-based tool that allows users to perform a visual exploratory data analysis, identification of important and significant features in given groups based on statistical tests, and de novo clustering on their data.
Related projects:	e-Infrastruktura CZ Advanced sequencing methods for deciphering structural variants in cancer genome Advanced molecular testing for aggregate diagnosis and management of DLBCL patients: engagement of gene expression profiling, liquid biopsy and long-read sequencing National institute for cancer research